Uganda Premier League champions Vipers SC have been drawn against 13-time Central African Republic League champions Real de Bangui in the first round of the qualifier games.
This was decided by a draw held on Tuesday in Cairo, Egypt.
The Kitende based team will visit Bangui between September 9-11 before the return leg in Uganda between September 16-18.
The winner on aggregate will face Congolese giants TP Mazembe in the second round.
TP Mazembe was excused from the first round.
If the Venoms make it past Mazembe, they will enter history books as the second Ugandan team to enter group CAF Champions League group stages, an honour that has been achieved by only KCCA FC.
But a defeat at the second round will see Vipers drop down to CAF Confederation Cup playoff stage.
